Succinic anhydride → 4-oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butanoic acid

Participants

Reaction Steps

A solution of 1-(2-pyridyl)piperazine (1.63 g) and succinic anhydride (1.1 g) in dimethylf ormamide (5 ml) was stirred for 24 hours at room temperature. The reaction mixture was reduced under reduced pressure and the concentrate was recrystallized from ethanol to give the titled compound (1.7 g) as a pale yellow crystal.

Provenance & Evidence