HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinic anhydride → GOLFKHJNLTVYSL-UHFFFAOYSA-N
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinic anhydride | HCID 7922 | — |
| Reactant | 1-(2-Pyrimidinyl)piperazine | HCID 88747 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | GOLFKHJNLTVYSL-UHFFFAOYSA-N | HCID 2815239 | 70.7% |
Reaction Steps
A solution of 1-(2-pyrimidinyl)piperazine (3.28 g) and succinic anhydride (2.2 g) in dimethylformamide (15 ml) was stirred for 1 hour at room temperature. The reaction mixture was concentrated under reduced pressure and the concentrate was recrystallized from ethanol/ethyl ether to give the titled compound (3.73 g) as a colorless crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242600B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-f99fd9744ddf4a91b410ac7ee12e96e7 |
| Source note | uspto-grants-2001_06 |