HCID 304320, compound → HCID 45490076, compound

HRID 1066565Notes

Reaction equation

HRID 1066565 reaction equation
[CH3:1][O:2][C:3](=[O:18])[C:4](=[CH:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=1)[CH2:5][C:6]([OH:8])=[O:7]>CO.[Pd]>[CH3:1][O:2][C:3](=[O:18])[CH:4]([CH2:9][C:10]1[CH:11]=[CH:12][C:13]([O:16][CH3:17])=[CH:14][CH:15]=1)[CH2:5][C:6]([OH:8])=[O:7]

Participants

4

Reactant 1

HCID 304320HCID 304320, compound

Product 1

HCID 45490076HCID 45490076, compoundYield 99.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of 2-(4-methoxybenzylidene)succinic acid 1-methyl ester (3 g) in methanol (100 ml) was added 10% palladium on carbon (0.6 g) and the solution was stirred for 16 hours under hydrogen atomosphere at room temperature. The catalyst was filtered off and the filtrate was concentrated under reduced pressure to give the titled compound (3 g) as a colorless oily substance.

Workup

  1. filtrationThe catalyst was filtered off
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-31e0d3b9f2914c0da178ac34b6cce0c9
Source dataset
uspto-grants-2001_06
Patent number
US06242600B1

Reaction notes

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