demeclocycline → HCID 131719400, compound

HRID 1066699Notes

Reaction equation

HRID 1066699 reaction equation
[CH3:1][N:2]([C@@H:4]1[C:22](=[O:23])[C:21]([C:24]([NH2:26])=[O:25])=[C:20]([OH:27])[C@:19]2([OH:28])[C@H:5]1[CH2:6][C@H:7]1[C:16]([C:17]2=[O:18])=[C:15]([OH:29])[C:14]2[C:9](=[C:10]([Cl:31])[CH:11]=[CH:12][C:13]=2[OH:30])[C@H:8]1[OH:32])[CH3:3]>CN1C(=O)CCC1>[CH3:3][N:2]([C@@H:4]1[C:22](=[O:23])[C:21]([C:24]([NH2:26])=[O:25])=[C:20]([OH:27])[C@:19]2([OH:28])[C@H:5]1[CH2:6][C@H:7]1[C:16]([C:17]2=[O:18])=[C:15]([OH:29])[C:14]2[C:9](=[C:10]([Cl:31])[CH:11]=[CH:12][C:13]=2[OH:30])[C@H:8]1[OH:32])[CH3:1].[CH3:3][N:2]1[C:24](=[O:25])[CH2:21][CH2:22][CH2:4]1

Participants

3

Reactant 1

HCID 54680690demeclocycline

Product 1

HCID 131719400HCID 131719400, compound

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

2.0 g of DMcT was dissolved into 7.0 g of NMP to obtain a DMcT-NMP solution. Into the solution, 0.5 g of metallic copper powder having an average particle size of 1 μm was added to give a mixture having a color of red slightly. Into the mixture, 1.0 g of the polyanline powder was added into the composition to dissolve. Further, 1.0 g of the sulfur powder was admixed thereto. The obtained mixture was applied on the foil of titanium having a thickness of 10 μm by means of an applicator with a gap of 150 μm and heating was carried out at 80° C. for 15 minutes under a stream of argon gas and, then, at 80° C. for 60 minutes under a reduced pressure of 1 cmHg to obtain a composite electrode having a thickness of 35 μm. The obtained composite electrode was cut to 2 cm×2 cm square. The amount of residual NMP in the composite electrode, which was calculated in the same manner as in EXAMPLE 2, was 0.05 wt % to 100 wt % of the amount of NMP.

Sources & evidence

ORD record
ord-c2b1b32fcf0d46febb39931b28994b3e
Source dataset
uspto-grants-2001_06
Patent number
US06245458B1

Reaction notes

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