化工社化工社 化学情報印刷レポート · 研究参考用
Sorbitan mono-(9Z)-9-octadecenoate → glycerol ascorbic acid Span 80
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sorbitan mono-(9Z)-9-octadecenoate | HCID 9920342 | — |
| 反応物 | L-Ascorbic Acid | HCID 54670067 | — |
| 反応物 | Ascorbic acid glycerol | HCID 131722625 | — |
| 溶媒 | Glycerol | HCID 753 | — |
| 生成物 | glycerol ascorbic acid Span 80 | HCID 131722624 | — |
反応手順
L-Ascorbic acid (50 mg) was dissolved in a 1 mL glycerol solution by heating and stirring the mixture. After being cooled to room temperature, the ascorbic acid/glycerol solution was mixed with GCSF powder (45.3 mg) and Span 80 (250 mL). 3.75 mL thickened oil (3% AIMS) prepared as described above was added to the G-CSF/ascorbic acid/glycerol mixture and ground together to give a viscous oil suspension (G-CSF/20% glycerol+ascorbic acid/Span 80/3% AIMS/oil).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06245740B1 |
| 出典データセット | uspto-grants-2001_06 |
| ORD ID | ord-ac8f2f07d82e4924bd96664d332a8bca |
| 出典メモ | uspto-grants-2001_06 |