HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 21196206, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 1-[1,4′-Bipiperidin]-1′-yl-2-[2-[(4-chlorophenoxy)methyl]-1-methyl-1H-indol-3-yl]-1,2-ethanedione | HCID 10625004 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21196206 | HCID 21196206 | — |
Reaction Steps
A round bottom flask under a nitrogen atmosphere was charged with 1-methyl-2-(4-chlorophenoxymethyl)-3-[2-[4-(piperidin-1-yl)piperidin-1-yl]-1,2-ethanedionyl]-1H-indole (0.1414 g, 0.282 mmol) and 2.8 ml of denatured ethanol. To this mixture was added sodium borohydride (0.064 g, 1.69 mmol). The reaction mixture was then stirred at room temperature overnight. The progress of the reaction was monitored by thin layer chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06245761B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-fb9944550bd6464ea7beb09ce6188552 |
| Source note | uspto-grants-2001_06 |