HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)-4-chloro-1-fluorobenzene → 4-(2-fluoro-5-chlorobenzyloxy)-N-(t-butoxycarbonyl)-N-(isopropyl)butylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)-4-chloro-1-fluorobenzene | HCID 2773626 | — |
| Reactant | 4-(2-fluorobenzyloxy)-N-(t-butoxycarbonyl)-N-(isopropyl)butylamine | HCID 21196084 | — |
| Product | 4-(2-fluoro-5-chlorobenzyloxy)-N-(t-butoxycarbonyl)-N-(isopropyl)butylamine | HCID 21196096 | — |
Reaction Steps
The title intermediate was prepared essentially as described supra for 4-(2-fluorobenzyloxy)-N-(t-butoxycarbonyl)-N-(isopropyl)butylamine, except that an equimolar amount of 2-fluoro-5-chlorobenzyl bromide was employed instead of the 2-fluorobenzyl bromide employed therein.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06245761B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-419cf5eeae8145e2ae6b3639ea531da1 |
| Source note | uspto-grants-2001_06 |