HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-amino-4-methyl-2,3-benzoxazin-1-one → 6-[3-(1-Phenyl-cyclopropyl)-2-oxo-propionylamino]-4-methyl-2,3-benzoxazin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-amino-4-methyl-2,3-benzoxazin-1-one | HCID 11182936 | — |
| Reactant | 2-Oxo-3-(1-phenylcyclopropyl)propanoic acid | HCID 18551253 | — |
| Reactant | 4-Bromo-6-(4-methyl-2-oxo-4-phenyl-valeroylamino)-phthalide | HCID 18551261 | — |
| Product | 6-[3-(1-Phenyl-cyclopropyl)-2-oxo-propionylamino]-4-methyl-2,3-benzoxazin-1-one | HCID 18551172 | — |
Reaction Steps
was obtained analogously to the process that is described for 4-bromo-6-(4-methyl-2-oxo-4-phenyl-valeroylamino)-phthalide from 6-amino-4-methyl-2,3-benzoxazin-1-one and 3-(1-phenyl-cyclopropyl)-2-oxo-propionic acid, melting point 197-200° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06245804B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-747644c5fc924cf0a8044d07602435f4 |
| Source note | uspto-grants-2001_06 |