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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1066943Generated: October 26, 2026

5-Aminophthalide → 5-[4-(4-Iodo-2-methoxyphenyl)-4-methyl-2-oxo-valeroylamino)-phthalide

https://huagongshe.com/reaction/1066943

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-AminophthalideHCID 720669—
Reactant4-(4-Iodo-2-methoxyphenyl)-4-methyl-2-oxovaleric acidHCID 18551190—
Reactant4-Bromo-5-(4-methyl-2-oxo-4-phenyl-valeroylamino)-phthalideHCID 18551202—
Product5-[4-(4-Iodo-2-methoxyphenyl)-4-methyl-2-oxo-valeroylamino)-phthalideHCID 18350627—

Reaction Steps

was obtained analogously to the process that is described for 4-bromo-5-(4-methyl-2-oxo-4-phenyl-valeroylamino)-phthalide from 5-aminophthalide and 4-(4-iodo-2-methoxyphenyl)-4-methyl-2-oxo-valeric acid as a foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06245804B1
Source datasetuspto-grants-2001_06
ORD IDord-84cd79c664fa420c8714738e14e778d1
Source noteuspto-grants-2001_06