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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1067136Generated: October 29, 2026

HCID 21196521, compound → HCID 21196496, compound

https://huagongshe.com/reaction/1067136

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21196521HCID 21196521—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
SolventEthyl AcetateHCID 8857—
ProductHCID 21196496HCID 2119649696.5%

Reaction Steps

To a solution of methyl 3-{[2-(4,5-diphenyloxazol-2-yl)-2-cyclohexen-1-yl]methyl}-2-methylbenzoate (119 mg) in EtOAc (8 m1) and MeOH (10 ml) was added 10% Pd/C (wet) (60 mg) and the mixture was stirred under hydrogen atmosphere at 3 atm at room temperature for 18 hours. The catalyst was removed by filtration and the filtrate was evaporated to give methyl 3-{[2-(4,5-diphenyloxazol-2-yl)-1-cyclohexyl]methyl}-2-methyl-benzoate (115.3 mg) as an amorphous solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06245790B1
Source datasetuspto-grants-2001_06
ORD IDord-1f44a40b56004824be47f0ca73a9746b
Source noteuspto-grants-2001_06