Triphenylphosphine → HCID 178506034, compound

HRID 1067153Notes

Reaction equation

HRID 1067153 reaction equation
[F:1][CH2:2][CH2:3][CH2:4][Br:5].[C:6]1([P:12]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>C1(C)C=CC=CC=1>[Br-:5].[F:1][CH2:2][CH2:3][CH2:4][PH:12]([C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1)([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 67699Propane, 1-bromo-3-fluoro-

Product 1

HCID 178506034HCID 178506034, compoundYield 85.2%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To 3 l of toluene was dissolved 200.0 g (1.42 mol) of 3-fluorobromopropane, 372 g (1.42 mol) of triphenylphosphine was added thereto, and refluxed for 15 hours. Deposited crystals were filtered off and subjected to suction drying to obtain 486 g (1.21 mol) of 3-fluoropropyltriphenylphosphine bromide. Yield of this compound from 3-fluorobromopropane was 85.2%.

Workup

  1. additionwas added
  2. temperaturerefluxed for 15 hours
  3. filtrationDeposited crystals were filtered off
  4. customdrying

Sources & evidence

ORD record
ord-d7973006a87c497a966e3fd56d572d6b
Source dataset
uspto-grants-2001_06
Patent number
US06248260B1

Reaction notes

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