Hydrochloric Acid → HCID 69837699, compound

HRID 1067298Notes

Reaction equation

HRID 1067298 reaction equation
[CH:1]([C:9]1[C:10]([NH:19][C:20](=[O:33])[C:21]2[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[C:23]([C:29]([F:32])([F:31])[F:30])[CH:22]=2)=[CH:11][CH:12]=[C:13]2[C:18]=1[CH2:17][NH:16][CH2:15][CH2:14]2)=[CH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[ClH:34].[CH3:35]O>>[ClH:34].[CH:1]([C:9]1[C:10]([NH:19][C:20](=[O:33])[C:21]2[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[C:23]([C:29]([F:31])([F:30])[F:32])[CH:22]=2)=[CH:11][CH:12]=[C:13]2[C:18]=1[CH2:17][N:16]([CH3:35])[CH2:15][CH2:14]2)=[CH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 54295335HCID 54295335, compound

Product 1

HCID 69837699HCID 69837699, compound

Procedure

The title compound (0.033 g) was prepared from N-(8-styryl-1,2,3,4-tetrahydroisoquinolin-7-yl)-4-methoxy-3-trifluoromethylbenzamide (0.068 g) according to the method of Example 3. The free base was converted into the hydrochloride salt by treatment of a methanol solution with excess ethereal HCl.

Sources & evidence

ORD record
ord-fa913dd7ae264cf6a0348ab5c2a4bca1
Source dataset
uspto-grants-2001_06
Patent number
US06248754B1

Reaction notes

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