HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → HCID 22386596, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2,4-Quinazolinediamine, 5-fluoro- | HCID 456246 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 22386596 | HCID 22386596 | 4.8% |
Reaction Steps
Aniline (Aldrich) (5 g, 50 mmol), sodium hydride (80% disp in mineral oil) (1.5 g, 50 mmol) and 2,4-diamino-5-fluoroquinazoline (4.4 g, 25 mmol) were reacted in 80 ml of dimethyl sulphoxide according to procedure A to give 2,4-diamino-5-anilinoquinazoline (0.3 g, 4.8%, m.p. 279-283° C. (dec)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248771B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-83479a61f3ec4ab0b3423a62074867d9 |
| Source note | uspto-grants-2001_06 |