Iodine → 1-[2-Oxo-2-(pyridin-2-yl)ethyl]pyridin-1-ium iodide

HRID 1067882Notes

Reaction equation

HRID 1067882 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)(=[O:3])[CH3:2].[I:10]I>N1C=CC=CC=1>[I-:10].[N:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[C:1](=[O:3])[CH2:2][N+:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:4]=1

Participants

4

Reactant 2

HCID 807IodineHCID 142862-Acetylpyridine

Product 1

HCID 2134991-[2-Oxo-2-(pyridin-2-yl)ethyl]pyridin-1-ium iodide

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a stirred solution of 2-acetylpyridine (0.5 mole) in 600 mL pyridine is added iodine (127 g; 0.5 mole). The mixture is heated on a steam bath for 45 minutes, and the product crystallizes on cooling. The solid is filtered and the crystalline cake is rinsed twice with methylene chloride.

Workup

  1. temperatureThe mixture is heated on a steam bath for 45 minutes
  2. customthe product crystallizes
  3. temperatureon cooling
  4. filtrationThe solid is filtered
  5. washthe crystalline cake is rinsed twice with methylene chloride

Sources & evidence

ORD record
ord-c43e95c0a52643d99b7885d936a465ba
Source dataset
uspto-grants-2001_06
Patent number
US06248870B1

Reaction notes

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