Thionyl Chloride → HCID 21195152, compound

HRID 1067892Notes

Reaction equation

HRID 1067892 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=3)[N:12]=[C:11]([C:21]3[CH:26]=[CH:25][CH:24]=[C:23]([C:27]([OH:29])=O)[N:22]=3)[CH:10]=2)=[CH:5][CH:4]=1.S(Cl)([Cl:32])=O>C(Cl)Cl>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=3)[N:12]=[C:11]([C:21]3[CH:26]=[CH:25][CH:24]=[C:23]([C:27]([Cl:32])=[O:29])[N:22]=3)[CH:10]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 21195145HCID 21195145, compound

Product 1

HCID 21195152HCID 21195152, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To 1 g of 4′-(4-methoxyphenyl)-2,2′:6′2″-terpyridine-6-carboxylic acid is added a solution of 1 mL of thionyl chloride in 25 mL of methylene chloride. The reaction mixture is heated gently for 1 hour, and the solvent and excess thionyl chloride are removed under reduced pressure. The crude product is triturated with anhydrous heptane and isolated by filtration under nitrogen.

Workup

  1. temperatureThe reaction mixture is heated gently for 1 hour
  2. customthe solvent and excess thionyl chloride are removed under reduced pressure
  3. customThe crude product is triturated with anhydrous heptane
  4. customisolated by filtration under nitrogen

Sources & evidence

ORD record
ord-8334bc69f48b4e4297de34eea8e68e58
Source dataset
uspto-grants-2001_06
Patent number
US06248870B1

Reaction notes

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