Dichlorodimethylsilane → Chloro(1H-inden-2-yl)dimethylsilane

HRID 1068058ノート

反応式

HRID 1068058 の反応式
Br[C:2]1[CH2:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.[Mg].[Cl:12][Si:13](Cl)([CH3:15])[CH3:14]>O1CCCC1>[Cl:12][Si:13]([C:2]1[CH2:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2)([CH3:15])[CH3:14]

参加物

5

反応物 3

HCID 6398DichlorodimethylsilaneHCID 5755861H-Indene, 2-bromo-HCID 5462224Magnesium

生成物 1

HCID 22395124Chloro(1H-inden-2-yl)dimethylsilane収率 110.2%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

2-Bromoindene (4.0 g, 0.02 mol.) was dissolved in 4 ml of tetrahydrofuran and added dropwise to a mixture consisting of magnesium (0.73 g, 0.03 mol.) and dichlorodimethylsilane (5.0 g, 0.04 mol.) in 4 ml of tetrahydrofuran. During the addition, the solution boiled slightly. After 15 hours' stirring, the volatile constituents were removed under an oil pump vacuum, and 40 ml of n-pentane were added to the residue. The resulting magnesium salt was filtered off with suction. The solvent was removed under an oil pump vacuum to yield 4.6 g (95%) of chloro-2-indenyl-dimethylsilane in the form of a colorless oil.

後処理

  1. additionadded dropwise to a mixture
  2. additionDuring the addition
  3. customthe volatile constituents were removed under an oil pump vacuum, and 40 ml of n-pentane
  4. additionwere added to the residue
  5. filtrationThe resulting magnesium salt was filtered off with suction
  6. customThe solvent was removed under an oil pump vacuum

出典と根拠

ORDレコード
ord-f52878d451504c13b7c798e321972fdf
出典データセット
uspto-grants-2001_06
特許番号
US06248912B1

反応ノート

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