HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium formate → HCID 15549372, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium formate | HCID 2723923 | — |
| Reactant | HCID 9905121 | HCID 9905121 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 15549372 | HCID 15549372 | 82.2% |
Reaction Steps
To a solution of 100 mg of 3-(1-benzyl-piperidin-4-yl)-3-H-quinazolin-4-one (from Step B) in 6 mL of MeOH was added 100 mg of ammonium formate followed by 100 mg of 10% palladium on carbon. After refluxing for 5 hours, the mixture was filtered through celite. Concentration under reduced pressure afforded 59 mg of the title compound as a foamy solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248755B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-d6e425786d30406596dc48a821cc58de |
| Source note | uspto-grants-2001_06 |