Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thiobenzamide | HCID 683563 | — |
| Reactant | HCID 21192975 | HCID 21192975 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21192967 | HCID 21192967 | 32.8% |
Reaction Steps
To 150 mg of 2-bromo-1-(1-benzoyl-4-piperidyl)-1-ethanone in 6 ml of EtOH was added 66 mg of thiobenzamide. The reaction was stirred at 80° C. for 2 hours. The solvent was evaporated under reduced pressure. The residue was purified by flash chromatography with 50% EtOAc in hexane to give 55 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06248755B1 |
|---|
| Source dataset | uspto-grants-2001_06 |
|---|
| ORD ID | ord-e65d7f51cdc34b3ab31746dd6b02233e |
|---|
| Source note | uspto-grants-2001_06 |
|---|
