Acetyl chloride → HCID 20481135, compound

Participants

Reaction Steps

To 2 mL of MeOH at 0° C. was added 0.17 mL of acetyl chloride. After warming to room temperature and stirring for 15 minutes, a solution of 71 mg (0.20 mmol) of 1-tert-butoxycarbonyl-4-((3-benzyl)phenyl)-piperidine (from Step E) was added. The reaction was stirred for 1 hour at room temperature. Volatiles were removed under reduced pressure to yield the title compound, which was used without further purification.

Provenance & Evidence