HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-N-ethylbenzamide → n-Ethyl-2-chloro-6-(ethenyldimethylsilyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-N-ethylbenzamide | HCID 347962 | — |
| Reactant | Chloro(dimethyl)vinylsilane | HCID 519368 | — |
| Product | n-Ethyl-2-chloro-6-(ethenyldimethylsilyl)benzamide | HCID 18630374 | — |
Reaction Steps
The title compound was prepared from the compound of Example f and 1.5 eq vinyldimethylsilyl chloride according to General Method C. Purification by HPLC with 1:4 ethyl acetate/hexanes gave 630 mg of the desired product as a white solid, a 9% yield. m.p. 86-89° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248894B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-d92c24af9b2a4212b69d6542ac3da283 |
| Source note | uspto-grants-2001_06 |