HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → N-ethyl-2-fluorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | 2-Fluorobenzoyl chloride | HCID 9808 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-ethyl-2-fluorobenzamide | HCID 3315690 | 87.8% |
Reaction Steps
2-Fluorobenzoyl chloride (2 g, 12.6 mmol) and 70% aq ethyl amine (1.78 g, 27.7 mmol) were combined in CH2Cl2 according to General Method E1, and kugelrohr distilled to give 1.85 g of N-ethyl-2-fluorobenzamide as a colorless oil, an 87% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248894B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-97d8af4143774d05b3208aaf4f206a1e |
| Source note | uspto-grants-2001_06 |