Hydrochloric Acid → HCID 21193372, compound

HRID 1068407Notes

Reaction equation

HRID 1068407 reaction equation
[C:1]([C:3]1[CH:17]=[CH:16][C:6]([CH2:7][N:8]2[C:12]([N+:13]([O-])=O)=[CH:11][N:10]=[CH:9]2)=[CH:5][CH:4]=1)#[N:2].[ClH:18]>[Pd]>[ClH:18].[C:1]([C:3]1[CH:4]=[CH:5][C:6]([CH2:7][N:8]2[C:12]([NH2:13])=[CH:11][N:10]=[CH:9]2)=[CH:16][CH:17]=1)#[N:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53889261HCID 53889261, compound

Product 1

HCID 21193372HCID 21193372, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A solution of 1-(4 cyanobenzyl)-5-nitro-1H-imidazole (100 mg, 0.438 mmol) and 10% palladium on carbon was hydrogenated in the presence of 1 equivalent of HCl under Parr conditions for 1 hr. Removal of the catalyst by filtration and evaporation of solvent in vacuo afforded the title compound.

Workup

  1. customRemoval of the catalyst
  2. filtrationby filtration and evaporation of solvent in vacuo

Sources & evidence

ORD record
ord-0635af67f7344aabb0238152da264316
Source dataset
uspto-grants-2001_06
Patent number
US06248756B1

Reaction notes

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