HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosulfonyl isocyanate → HCID 54024967, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosulfonyl isocyanate | HCID 70918 | — |
| Reactant | HCID 21193317 | HCID 21193317 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 54024967 | HCID 54024967 | — |
Reaction Steps
To a cold (5° C.) solution of chlorosulfonyl isocyanate in THF, anhydrous formic acid is added (Journal of Organic Chemistry, vol 54, page 5825,(1989)). The resultant mixture is stirred until gas evolution ceased, and treated with a solution of 1-benzyl-4-(3-methylphenylamino)-4-aminomethylpiperidine in THF. The mixture is stirred at room temp. overnight to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248756B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-01dfed75a3444df3bf8603f5adc591fc |
| Source note | uspto-grants-2001_06 |