HCID 21190028, compound → 4-Fluoro-2,6-dinitroaniline

HRID 1068596Notes

Reaction equation

HRID 1068596 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[C:5]([NH:11]C(=O)C(F)(F)F)=[C:4]([N+:18]([O-:20])=[O:19])[CH:3]=1>C([O-])([O-])=O.[K+].[K+]>[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[C:5]([NH2:11])=[C:4]([N+:18]([O-:20])=[O:19])[CH:3]=1

Participants

3

Reactant 1

HCID 21190028HCID 21190028, compound

Product 1

HCID 3453624-Fluoro-2,6-dinitroanilineYield 52.2%

Reagents, catalysts & solvents 1

HCID 11430Potassium CarbonateSolvent

Procedure

A solution of 4-fluoro-2,6-dinitro(trifluoroacetamido)benzene (297 mg, 1.00 mmol) in 10% K2CO3 (10 mL) was refluxed for 1 h, then cooled to room temperature to give yellow crystals. It was filtered and washed with cold water (2×1 mL), affording 105 mg (52%) of the title compound. 1H NMR (DMSO-d6): δ 8.254 (s, 2H), 8.460 (d, 2H, J=8.4).

Workup

  1. customto give yellow crystals
  2. filtrationIt was filtered
  3. washwashed with cold water (2×1 mL)

Sources & evidence

ORD record
ord-ff27cee7b69e4000804cd0cd16852c01
Source dataset
uspto-grants-2001_06
Patent number
US06251903B1

Reaction notes

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