Hydrochloric Acid → HCID 21190104, compound

HRID 1068695Notes

Reaction equation

HRID 1068695 reaction equation
[ClH:1].[F:2][C:3]([F:26])([F:25])[S:4]([NH:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]1[CH2:23][C:22]2[N:24]3[C:15](=[CH:16][N:17]=[C:18]3[CH:19]=[CH:20][CH:21]=2)[CH2:14]1)(=[O:6])=[O:5]>C(O)C>[ClH:1].[ClH:1].[F:25][C:3]([F:2])([F:26])[S:4]([NH:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]1[CH2:23][C:22]2[N:24]3[C:15](=[CH:16][N:17]=[C:18]3[CH:19]=[CH:20][CH:21]=2)[CH2:14]1)(=[O:5])=[O:6]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190105HCID 21190105, compound

Product 1

HCID 21190104HCID 21190104, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a solution consisting of 10 ml of ethanol and 0.5 ml of 12N HCl was dissolved 0.88 g (2.34 mmol) of 4,5-dihydro-4-[5-(trifluoromethanesulfonamido)pentan-1-yl]-3H-1,4,8b-triazaacenaphthylene. The solvent was distilled off under reduced pressure to leave 1.05 g of the desired compound (100%, white amorphous).

Workup

  1. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-4eb2d8ff1ece4473b50dd4ff393b910b
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

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