Hydrochloric Acid → HCID 21190134, compound

HRID 1068705Notes

Reaction equation

HRID 1068705 reaction equation
[ClH:1].[C:2]1([C:8]2[N:9]=[C:10]3[N:19]4[C:14]([CH2:15][N:16]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][NH:25][S:26]([C:29]([F:32])([F:31])[F:30])(=[O:28])=[O:27])[CH2:17][C:18]=24)=[CH:13][CH:12]=[CH:11]3)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C>[ClH:1].[ClH:1].[C:2]1([C:8]2[N:9]=[C:10]3[N:19]4[C:14]([CH2:15][N:16]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][NH:25][S:26]([C:29]([F:30])([F:31])[F:32])(=[O:28])=[O:27])[CH2:17][C:18]=24)=[CH:13][CH:12]=[CH:11]3)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190135HCID 21190135, compound

Product 1

HCID 21190134HCID 21190134, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a solution consisting of 5 ml of ethanol and 0.1 ml of 12N HCl was dissolved 254 mg (0.56 mmol) of 4,5-dihydro-2-phenyl-4-[5-(trifluoromethanesulfonamido)pentan-1-yl]-3H-1,4,8b-triazaacenaphthylene. The solvent was distilled under reduced pressure to give 295 mg of the desired compound (100%, white amorphous).

Workup

  1. distillationThe solvent was distilled under reduced pressure

Sources & evidence

ORD record
ord-3466819a16cf46d19932ee138f911ec7
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

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