Hydrochloric Acid → HCID 9801812, compound

HRID 1068707Notes

Reaction equation

HRID 1068707 reaction equation
[F:1][C:2]([F:25])([F:24])[S:3]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH2:21][C:20]2[N:22]3[C:13](=[CH:14][N:15]=[C:16]3[CH:17]=[CH:18][CH:19]=2)[C:12]1=[O:23])(=[O:5])=[O:4].[ClH:26]>C(O)C>[ClH:26].[F:24][C:2]([F:1])([F:25])[S:3]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH2:21][C:20]2[N:22]3[C:13](=[CH:14][N:15]=[C:16]3[CH:17]=[CH:18][CH:19]=2)[C:12]1=[O:23])(=[O:4])=[O:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 9801813HCID 9801813, compound

Product 1

HCID 9801812HCID 9801812, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a mixture of 50 ml of ethanol and 1 ml of 12N HCl was dissolved 2.87 g (7.63 mmol) of 4,5-dihydro-4-[4-(trifluoromethanesulfonamido)butan-1-yl]-3H-1,4,8b-triazaacenaphthylen-3-one, and the solvent was distilled off under reduced pressure to leave 3.15 g of the desired compound (100%, pale yellow solid matter).

Workup

  1. distillationthe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-ed6ae331d069499bbd0bb491c33489e3
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

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