Hydrochloric Acid → HCID 21190195, compound

HRID 1068710Notes

Reaction equation

HRID 1068710 reaction equation
[ClH:1].[F:2][C:3]([F:25])([F:24])[S:4]([NH:7][CH2:8][CH2:9][CH2:10][N:11]1[CH2:21][C:20]2[N:22]3[C:13](=[CH:14][N:15]=[C:16]3[CH:17]=[CH:18][CH:19]=2)[C:12]1=[O:23])(=[O:6])=[O:5]>C(O)C>[ClH:1].[F:24][C:3]([F:2])([F:25])[S:4]([NH:7][CH2:8][CH2:9][CH2:10][N:11]1[CH2:21][C:20]2[N:22]3[C:13](=[CH:14][N:15]=[C:16]3[CH:17]=[CH:18][CH:19]=2)[C:12]1=[O:23])(=[O:5])=[O:6]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 11013897HCID 11013897, compound

Product 1

HCID 21190195HCID 21190195, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a mixture solution consisting of 5 ml of ethanol and 0.1 ml of 12N HCl was dissolved 145 mg (0.40 mmol) of 4,5-dihydro-4-[3-(trifluoromethanesulfonamido)propan-1-yl]-3H-1,4,8b-triazaacenaphthylen-3-one. The solvent was distilled off under reduced pressure to leave 160 mg of the desired compound (100%, pale yellow solid substance).

Workup

  1. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-e06b3255f5734691aec084f0f88ec460
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

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