Hydrochloric Acid → HCID 21190166, compound

HRID 1068713Notes

Reaction equation

HRID 1068713 reaction equation
[ClH:1].[F:2][C:3]([F:27])([F:26])[S:4]([NH:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]1[CH2:23][C:22]2[N:24]3[C:15](=[CH:16][N:17]=[C:18]3[CH:19]=[CH:20][CH:21]=2)[C:14]1=[O:25])(=[O:6])=[O:5]>C(O)C>[ClH:1].[F:26][C:3]([F:2])([F:27])[S:4]([NH:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]1[CH2:23][C:22]2[N:24]3[C:15](=[CH:16][N:17]=[C:18]3[CH:19]=[CH:20][CH:21]=2)[C:14]1=[O:25])(=[O:5])=[O:6]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190167HCID 21190167, compound

Product 1

HCID 21190166HCID 21190166, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a mixture solvent consisting of 5 ml of ethanol and 0.1 ml of 12N HCl was dissolved 593 mg (1.52 mmol) of 4,5-dihydro-4-[5-(trifluoromethanesulfonamido)pentan-1-yl]-3H-1,4,8b-triazaacenaphthylene-3-one. The solvent was distilled off under reduced pressure to leave 650 mg of the desired compound (100%, pale yellow solid).

Workup

  1. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-8b6e8051678f461f9904ef54a23e0e9a
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

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