Hydrochloric Acid → HCID 21190269, compound

HRID 1068715Notes

Reaction equation

HRID 1068715 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]2[N:13]3[C:8]([CH2:9][N:10]([CH2:15][CH2:16][CH2:17][CH2:18][NH:19][S:20]([C:23]([F:26])([F:25])[F:24])(=[O:22])=[O:21])[C:11](=[O:14])[C:12]=13)=[CH:7][CH:6]=[CH:5]2.[ClH:27]>C(O)C>[ClH:27].[CH3:1][C:2]1[N:3]=[C:4]2[N:13]3[C:8]([CH2:9][N:10]([CH2:15][CH2:16][CH2:17][CH2:18][NH:19][S:20]([C:23]([F:26])([F:25])[F:24])(=[O:21])=[O:22])[C:11](=[O:14])[C:12]=13)=[CH:7][CH:6]=[CH:5]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190262HCID 21190262, compound

Product 1

HCID 21190269HCID 21190269, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

234 mg (0.6 mmol) of 4,5-dihydro-2-methyl-4-[4-(trifluoromethanesulfonamido)butan-1-yl]-3H-1,4,8b-triazaacenaphthylen-3-one was dissolved in a mixture solvent consisting of 2 ml of ethanol and 0.05 ml of 12N HCl. The solvent was distilled off under reduced pressure to leave 256 mg of the desired compound (100%, pale yellow solid substance).

Workup

  1. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-9743ded6c6c842378e883f85d5dc8da0
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

Loading…