Hydrochloric Acid → HCID 21190088, compound

HRID 1068718Notes

Reaction equation

HRID 1068718 reaction equation
[ClH:1].[CH2:2]([C:4]1[N:5]=[C:6]2[N:15]3[C:10]([CH2:11][N:12]([CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][NH:22][S:23]([C:26]([F:29])([F:28])[F:27])(=[O:25])=[O:24])[C:13](=[O:16])[C:14]=13)=[CH:9][CH:8]=[CH:7]2)[CH3:3]>C(O)C>[ClH:1].[CH2:2]([C:4]1[N:5]=[C:6]2[N:15]3[C:10]([CH2:11][N:12]([CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][NH:22][S:23]([C:26]([F:28])([F:27])[F:29])(=[O:24])=[O:25])[C:13](=[O:16])[C:14]=13)=[CH:9][CH:8]=[CH:7]2)[CH3:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190089HCID 21190089, compound

Product 1

HCID 21190088HCID 21190088, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a mixture solvent consisting of 2 ml of ethanol and 0.05 ml of 12N HCl was dissolved 110 mg (0.26 mmol) of 4,5-dihydro-2-ethyl-4-[5-(trifluoromethanesulfonamido)pentan-1-yl]-3H-1,4,8b-triazaacenaphthylen-3-one. The solvent was distilled off under reduced pressure to leave 120 mg of the desired compound (100%, pale yellow solid).

Workup

  1. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-63b6598fe86a4d86bcdcb39c48b054fd
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

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