Hydrochloric Acid → HCID 70214383, compound

HRID 1068738Notes

Reaction equation

HRID 1068738 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]2[CH:12]=[CH:11][CH:10]=[C:9]3[N:5]2[C:6]=1[C:7](=[O:26])[N:8]3[CH2:13][CH2:14][CH:15]([NH:17][S:18]([CH2:21][C:22]([F:25])([F:24])[F:23])(=[O:20])=[O:19])[CH3:16].[ClH:27]>CO>[ClH:27].[CH3:1][C:2]1[N:3]=[C:4]2[CH:12]=[CH:11][CH:10]=[C:9]3[N:5]2[C:6]=1[C:7](=[O:26])[N:8]3[CH2:13][CH2:14][CH:15]([NH:17][S:18]([CH2:21][C:22]([F:23])([F:24])[F:25])(=[O:19])=[O:20])[CH3:16]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70212372HCID 70212372, compound

Product 1

HCID 70214383HCID 70214383, compoundYield 99.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 840 mg (2.15 mmol) of 1,2-dihydro-3-methyl-1-[3-[(2,2,2-trifluoro)ethanesulfonamido]butan-1-yl]-1,4,7b-triazacyclopent[cd]inden-2-one in 10 ml of methanol was added 0.22 ml of conc. HCl. The solvent was distilled off, and the residue was washed with acetone-ether to give 915 mg of the desired compound (99.7%, colorless solid), m.p.116.0-118° C.

Workup

  1. distillationThe solvent was distilled off
  2. washthe residue was washed with acetone-ether

Sources & evidence

ORD record
ord-ac5e4d86edac4b38b6c3105ee36bb750
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

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