Sodium Acetate → HCID 86752511, compound

HRID 1069131Notes

Reaction equation

HRID 1069131 reaction equation
[C:1]1([C:7]2[CH:8]=[C:9]([CH2:13][O:14][C:15]3[CH:22]=[CH:21][C:18]([CH:19]=O)=[CH:17][CH:16]=3)[CH:10]=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([O-])(=O)C.[Na+].[S:28]1[CH2:34][C:32](=[O:33])[NH:31][C:29]1=[S:30]>C(O)(=O)C>[C:1]1([C:7]2[CH:8]=[C:9]([CH2:13][O:14][C:15]3[CH:22]=[CH:21][C:18]([CH:19]=[C:34]4[S:28][C:29](=[S:30])[NH:31][C:32]4=[O:33])=[CH:17][CH:16]=3)[CH:10]=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 1201546RhodanineHCID 21191275HCID 21191275, compound

Product 1

HCID 86752511HCID 86752511, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Under a nitrogen atmosphere in a round bottom flask 4-[(3-phenylphenyl)methoxy]benzaldehyde (3.2 g, 10 mmol) was dissolved in acetic acid. To this solution, while stirring, were added sodium acetate (2.87 g, 35 mmol) and rhodanine (1.33 g, 10 mmol). This mixture was heated to reflux and maintained at this temperature. The progress of this reaction was monitored by thin layer chromatography.

Workup

  1. temperatureThis mixture was heated
  2. temperatureto reflux
  3. temperaturemaintained at this temperature

Sources & evidence

ORD record
ord-f3071acb18a34952870f4adc7a765a78
Source dataset
uspto-grants-2001_06
Patent number
US06251928B1

Reaction notes

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