Sodium Acetate → HCID 86752516, compound

HRID 1069138Notes

Reaction equation

HRID 1069138 reaction equation
[F:1][C:2]([F:20])([F:19])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][O:10][C:11]1[CH:18]=[CH:17][C:14]([CH:15]=O)=[CH:13][CH:12]=1.C([O-])(=O)C.[Na+].[S:26]1[CH2:32][C:30](=[O:31])[NH:29][C:27]1=[S:28]>C(O)(=O)C>[F:1][C:2]([F:20])([F:19])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][O:10][C:11]1[CH:18]=[CH:17][C:14]([CH:15]=[C:32]2[S:26][C:27](=[S:28])[NH:29][C:30]2=[O:31])=[CH:13][CH:12]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 1201546RhodanineHCID 211912844-[[2-(Trifluoromethyl)phenyl]methoxy]benzaldehyde

Product 1

HCID 86752516HCID 86752516, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Under a nitrogen atmosphere in a round bottom flask 4-[(2-trifluoromethylphenyl)methoxy]benzaldehyde (2.98 g, 10.63 mmol), sodium acetate (3.05 g, 37.2 mmol), and rhodanine (1.42 g, 10.7 mmol) were dissolved in 53 ml of acetic acid. The reaction solution was then heated to reflux and maintained at this temperature for about three days.

Workup

  1. temperatureThe reaction solution was then heated
  2. temperatureto reflux
  3. temperaturemaintained at this temperature for about three days

Sources & evidence

ORD record
ord-4a5b2821e7f440e09b333fd7276c3244
Source dataset
uspto-grants-2001_06
Patent number
US06251928B1

Reaction notes

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