Hydrochloric Acid → HCID 54696200, compound

HRID 1069425Notes

Reaction equation

HRID 1069425 reaction equation
Cl.[OH:2][C:3]1[CH:8]=[C:7]([CH3:9])[N:6]([CH2:10][C:11]([OH:13])=[O:12])[C:5](=[O:14])[C:4]=1[N+:15]([O-:17])=[O:16].[CH3:18]O>>[OH:2][C:3]1[CH:8]=[C:7]([CH3:9])[N:6]([CH2:10][C:11]([O:13][CH3:18])=[O:12])[C:5](=[O:14])[C:4]=1[N+:15]([O-:17])=[O:16]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 54713227HCID 54713227, compound

Product 1

HCID 54696200HCID 54696200, compoundYield 85%

Procedure

250 ml of methanol are saturated with a gaseous hydrochloric acid stream and 25 g (0.11 mol) of 4-hydroxy-6-methyl-3-nitro-2-oxo-1,2-dihydropyridine-1-acetic acid are introduced in portions. The mixture is heated at reflux temperature for 4 hours and then the precipitate is filtered and it is dried in an oven. 23 g of product are obtained in the form of yellow crystals.

Workup

  1. additionare introduced in portions
  2. temperatureThe mixture is heated
  3. temperatureat reflux temperature for 4 hours
  4. filtrationthe precipitate is filtered
  5. customit is dried in an oven

Sources & evidence

ORD record
ord-47d318e66a824c00b53faf4c9e3cf548
Source dataset
uspto-grants-2001_06
Patent number
US06252082B1

Reaction notes

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