3-(Bromomethyl)thiophene → HCID 86757061, compound

HRID 1069429Notes

Reaction equation

HRID 1069429 reaction equation
[CH3:1][C:2]1[N:7]([CH2:8][C:9]([O:11][CH3:12])=[O:10])[C:6](=[O:13])[C:5]([N+:14]([O-:16])=[O:15])=[C:4](OS(C(F)(F)F)(=O)=O)[CH:3]=1.Br[CH2:26][C:27]1[CH:31]=[CH:30][S:29][CH:28]=1>>[CH3:1][C:2]1[N:7]([CH2:8][C:9]([O:11][CH3:12])=[O:10])[C:6](=[O:13])[C:5]([N+:14]([O-:16])=[O:15])=[C:4]([CH2:26][C:27]2[CH:31]=[CH:30][S:29][CH:28]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 5207033-(Bromomethyl)thiopheneHCID 11079278Methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)sulphonyl]oxy]-1,2-dihydropyridine-1-acetate

Product 1

HCID 86757061HCID 86757061, compoundYield 84%

Procedure

This compound is prepared from 5 g (13.4 mmol) of methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)sulphonyl]oxy]-1,2-dihydropyridine-1-acetate and 2.9 g (16.4 mmol) of 3-bromomethyl-thiophene according to the method described in 1.5. 3.5 g of product are obtained in the form of yellow crystals.

Sources & evidence

ORD record
ord-52154b046f5e4bb49c64002c3b9a5864
Source dataset
uspto-grants-2001_06
Patent number
US06252082B1

Reaction notes

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