1-(Bromomethyl)-4-(1,1-dimethylethyl)benzene → HCID 70186997, compound

HRID 1069430Notes

Reaction equation

HRID 1069430 reaction equation
[CH3:1][C:2]1[N:7]([CH2:8][C:9]([O:11][CH3:12])=[O:10])[C:6](=O)[C:5]([N+:14]([O-:16])=[O:15])=[C:4](OS(C(F)(F)F)(=O)=O)[CH:3]=1.[CH3:25][C:26]([C:29]1[CH:34]=[CH:33][C:32]([CH2:35]Br)=[CH:31][CH:30]=1)([CH3:28])[CH3:27]>>[CH3:28][C:26]([C:29]1[CH:30]=[CH:31][C:32]([CH2:35][C:4]2[CH:3]=[C:2]([CH3:1])[N:7]([CH2:8][C:9]([O:11][CH3:12])=[O:10])[CH2:6][C:5]=2[N+:14]([O-:16])=[O:15])=[CH:33][CH:34]=1)([CH3:25])[CH3:27]

Participants

3

Reactant 2

HCID 878361-(Bromomethyl)-4-(1,1-dimethylethyl)benzeneHCID 11079278Methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)sulphonyl]oxy]-1,2-dihydropyridine-1-acetate

Product 1

HCID 70186997HCID 70186997, compoundYield 72.9%

Procedure

This compound is prepared from 5 g (13.4 mmol) of methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)sulphonyl]oxy]-1,2-dihydropyridine-1-acetate and 4.54 g (20 mmol) of 4-(1,1-dimethylethyl)phenylmethyl bromide according to the method described in 1.5. 3.5 g of product are obtained in the form of yellow crystals.

Sources & evidence

ORD record
ord-cea58c8bff1b45dca0e0f085486f4d2d
Source dataset
uspto-grants-2001_06
Patent number
US06252082B1

Reaction notes

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