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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1069435Generated: October 29, 2026

(Iodomethyl)cyclohexane → Methyl 4-(cyclohexylmethyl)-6-methyl-3-nitro-2-oxo-1,2-dihydropyridine-1-acetate

https://huagongshe.com/reaction/1069435

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Iodomethyl)cyclohexaneHCID 230414—
ReactantMethyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)sulphonyl]oxy]-1,2-dihydropyridine-1-acetateHCID 11079278—
ProductMethyl 4-(cyclohexylmethyl)-6-methyl-3-nitro-2-oxo-1,2-dihydropyridine-1-acetateHCID 8675706550.4%

Reaction Steps

This compound is prepared from 3 g (8 mmol) of methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)-sulphonyl]oxy]-1,2-dihydropyridine-1-acetate and 5.45 g (24.3 mmol) of cyclohexylmethyl iodide according to the method described in Example 1.5. 1.3 g of product are obtained in the form of yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06252082B1
Source datasetuspto-grants-2001_06
ORD IDord-ce66c34ac387473aa1ad3342ba4f2767
Source noteuspto-grants-2001_06