HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Iodomethyl)cyclohexane → Methyl 4-(cyclohexylmethyl)-6-methyl-3-nitro-2-oxo-1,2-dihydropyridine-1-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Iodomethyl)cyclohexane | HCID 230414 | — |
| Reactant | Methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)sulphonyl]oxy]-1,2-dihydropyridine-1-acetate | HCID 11079278 | — |
| Product | Methyl 4-(cyclohexylmethyl)-6-methyl-3-nitro-2-oxo-1,2-dihydropyridine-1-acetate | HCID 86757065 | 50.4% |
Reaction Steps
This compound is prepared from 3 g (8 mmol) of methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)-sulphonyl]oxy]-1,2-dihydropyridine-1-acetate and 5.45 g (24.3 mmol) of cyclohexylmethyl iodide according to the method described in Example 1.5. 1.3 g of product are obtained in the form of yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06252082B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-ce66c34ac387473aa1ad3342ba4f2767 |
| Source note | uspto-grants-2001_06 |