Ammonia → HCID 86757066, compound

HRID 1069438Notes

Reaction equation

HRID 1069438 reaction equation
C([N:4]([C:8]1[CH:13]=[CH:12][C:11]([CH2:14]Br)=[CH:10][CH:9]=1)[C:5](=[O:7])[CH3:6])(=O)C.[CH3:16][C:17]1[N:22]([CH2:23][C:24]([O:26][CH3:27])=[O:25])[C:21](=[O:28])[C:20]([N+:29]([O-:31])=[O:30])=[C:19](OS(C(F)(F)F)(=O)=O)[CH:18]=1.N>>[C:5]([NH:4][C:8]1[CH:9]=[CH:10][C:11]([CH2:14][C:19]2[CH:18]=[C:17]([CH3:16])[N:22]([CH2:23][C:24]([O:26][CH3:27])=[O:25])[C:21](=[O:28])[C:20]=2[N+:29]([O-:31])=[O:30])=[CH:12][CH:13]=1)(=[O:7])[CH3:6]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 11079278Methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)sulphonyl]oxy]-1,2-dihydropyridine-1-acetateHCID 21191804HCID 21191804, compound

Product 1

HCID 86757066HCID 86757066, compound

Procedure

It is prepared from 7.3 g (27 mmol) of N-acetyl-N-[4-(bromomethyl)phenyl]acetamide and 4 g (13.4 mmol) of methyl 6-methyl-3-nitro-2-oxo-4-[[(trifluoromethyl)sulphonyl]oxy]-1,2-dihydropyridine-1-acetate. The crude product is treated with ammonia.

Sources & evidence

ORD record
ord-2bab55dab9524b6e9771662d638c9537
Source dataset
uspto-grants-2001_06
Patent number
US06252082B1

Reaction notes

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