Benzyl chloroformate → HCID 70186119, compound

HRID 1069440Notes

Reaction equation

HRID 1069440 reaction equation
[NH2:1][C:2]1[C:3](=[O:21])[N:4]([CH2:16][C:17]([O:19][CH3:20])=[O:18])[C:5]([CH3:15])=[CH:6][C:7]=1[O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.Cl[C:23]([O:25][CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=[O:24]>>[CH3:15][C:5]1[N:4]([CH2:16][C:17]([O:19][CH3:20])=[O:18])[C:3](=[O:21])[C:2]([NH:1][C:23]([O:25][CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[O:24])=[C:7]([O:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=1

Participants

3

Reactant 2

HCID 10387Benzyl chloroformateHCID 70185217HCID 70185217, compound

Product 1

HCID 70186119HCID 70186119, compound

Procedure

2.5 g (7.9 mmol) of methyl 3-amino-6-methyl-2-oxo-4-phenoxy-1,2-dihydropyridine-1-acetate are treated with 1.7 ml (11.9 mmol) of phenylmethyl chloroformate under the conditions of Example 3.

Sources & evidence

ORD record
ord-ab03a6d5ee494eacb5d27050790b76de
Source dataset
uspto-grants-2001_06
Patent number
US06252082B1

Reaction notes

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