HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Acetylbenzoic Acid → 4-{3E-[2,4-Dimethoxy-5-(2H-tetrazol-5-yl)-phenyl]-acryloyl}-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Acetylbenzoic Acid | HCID 11470 | — |
| Reactant | 2,4-dimethoxy-5-(2H-tetrazol-5-yl)-benzaldehyde | HCID 21981081 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-{3E-[2,4-Dimethoxy-5-(2H-tetrazol-5-yl)-phenyl]-acryloyl}-benzoic acid | HCID 10126430 | 19% |
Reaction Steps
The title compound was prepared by condensing 2,4-dimethoxy-5-(2H-tetrazol-5-yl)-benzaldehyde (Ex-75A) and 4-acetylbenzoic acid in a similar manner as described in Ex-3. Yellow solid, 19% yield, mp 218° C. (dec). 1H-NMR (DMSO-d6) δ 8.58 (s, 1H), 8.20 (d, 2H), 8.03 (m, 3H), 7.85 (d, 1H), 6.90 (s, 1H), 4.04 (s, 3H), 4.02 (s, 3H). MS m/z=422 ([M+CH3CN+H]+, 100%). HRMS m/z: calc. 381.1199, found 381.1184.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07094801B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-1a106097291b4be188bdf9f422a00973 |
| Source note | uspto-grants-2006_08 |