Tetrahydrofuran → 1-(4-Chloro-2-fluorophenyl)-2,2,2-trifluoroethan-1-one
Reaction equation
[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[Cl:6][c:7]1[cH:8][c:9]([F:14])[c:10]([I:13])[cH:11][cH:12]1.[F:15][C:16]([C:17](=[O:18])[O:19][CH2:20][CH3:21])([F:22])[F:23]>>[Cl:6][c:7]1[cH:8][c:9]([F:14])[c:10]([C:17]([C:16]([F:15])([F:22])[F:23])=[O:18])[cH:11][cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-0ebbe9b62f554c0f92924f666a635675
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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