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HRID1070528

反应详情

EQUATION

反应方程式

HRID 1070528 的结构方程式

REACTANTS

反应物

2
结构：OCc1ccncc1
HCID11472

4-Pyridinemethanol

C6H7NO

结构：Clc1ccc(Nc2nnc(Cl)c3ccccc23)cc1
HCID12075649

1-chloro-4-(4-chlorophenylamino)-phthalazine

C14H9Cl2N3

PRODUCTS

生成物

1
结构：Clc1ccc(Nc2nnc(OCc3ccncc3)c3ccccc23)cc1
HCID22397275

N-(4-Chlorophenyl)-4-[(pyridin-4-yl)methoxy]phthalazin-1-amine

C20H15ClN4O

收率 87%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O.ClCCl
溶剂HCID21584124

Propan-2-one--dichloromethane (1/1)

C4H8Cl2O

PROCEDURE

实验过程

The general procedure used for the preparation of Example 3 was used in step 1 of the preparation of Example 4 from 1-chloro-4-(4-chlorophenylamino)phthalazine and 4-pyridyl-carbinol; (87% yield). TLC (20% acetone/dichloromethane): Rf=0.26.

WORKUP

后处理

  1. customThe general procedure used for the preparation of Example 3