Benzoyl chloride → HCID 22397381, compound

HRID 1070667Notes

Reaction equation

HRID 1070667 reaction equation
[Cl-].[Al+3].[Cl-].[Cl-].[CH3:5][O:6][C:7]1[C:16]([O:17][CH3:18])=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=1.[C:19](Cl)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>C(Cl)Cl>[CH3:18][O:17][C:16]1[CH:15]=[C:14]2[C:9](=[CH:8][C:7]=1[O:6][CH3:5])[CH:10]=[C:11]([C:19]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:26])[CH:12]=[CH:13]2

Participants

5

Reactant 3

HCID 7412Benzoyl chlorideHCID 6047082,3-DimethoxynaphthaleneHCID 6451240Aluminum(III) Chloride

Product 1

HCID 22397381HCID 22397381, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Aluminum chloride (16.0 g) was added to a solution of 2,3-dimethoxynaphthalene (18.0 g) and benzoylchloride (12.0 g) in cold methylene chloride (400 ml) and the solution was stirred overnight. After treatment with cold water the phases were separated and the methylene chloride phase washed with 1 M sodium hydroxide. The product was triturated with warm ether. Yield: 7 g, melting point 124-125° C.

Workup

  1. customAfter treatment with cold water the phases were separated
  2. washthe methylene chloride phase washed with 1 M sodium hydroxide
  3. customThe product was triturated with warm ether

Sources & evidence

ORD record
ord-97200d0443444a6287e67301b6d87977
Source dataset
uspto-grants-2005_06
Patent number
US06903114B2

Reaction notes

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