Palmitoyl chloride → HCID 22397410, compound

HRID 1070669Notes

Reaction equation

HRID 1070669 reaction equation
[CH3:1][O:2][C:3]1[C:12]([O:13][CH3:14])=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1.[C:15](Cl)(=[O:31])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]C.[Cl-].[Al+3].[Cl-].[Cl-]>C(Cl)Cl>[CH3:14][O:13][C:12]1[CH:11]=[C:10]2[C:5](=[CH:4][C:3]=1[O:2][CH3:1])[CH:6]=[C:7]([C:15](=[O:31])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH:8]=[CH:9]2

Participants

5

Reactant 3

HCID 8206Palmitoyl chlorideHCID 6047082,3-DimethoxynaphthaleneHCID 6451240Aluminum(III) Chloride

Product 1

HCID 22397410HCID 22397410, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The solution of 2,3-dimethoxynaphthalene (1.9 g), palmitoyl chloride (3.2 ml) and aluminium chloride (1.5 g) in methylene chloride (40 ml) was stirred at ambient temperature overnight. The reaction mixture was worked up as described in example 4(a). The crude product was recrystallized from ethyl acetate-heptane. Yield 2.0 g.

Workup

  1. customThe crude product was recrystallized from ethyl acetate-heptane

Sources & evidence

ORD record
ord-47e36acc28a4494598d8aa5e04bc0cdd
Source dataset
uspto-grants-2005_06
Patent number
US06903114B2

Reaction notes

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