Hydrazine hydrate (1:1) → HCID 53680566, compound

HRID 1070760Notes

Reaction equation

HRID 1070760 reaction equation
[C:1]1([CH:7]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[N:8]2[CH2:13][CH2:12][N:11]([S:14]([CH2:17][CH2:18][CH2:19][N:20]3C(=O)C4C(=CC=CC=4)C3=O)(=[O:16])=[O:15])[CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.NN.O>>[C:31]1([CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[N:8]2[CH2:9][CH2:10][N:11]([S:14]([CH2:17][CH2:18][CH2:19][NH2:20])(=[O:16])=[O:15])[CH2:12][CH2:13]2)[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 22397655HCID 22397655, compound

Product 1

HCID 53680566HCID 53680566, compound

Procedure

Batch size: 149 (27.8 mmol) 2-[3-(4-diphenylmethyl-piperazin-1-yl-sulfonyl)-propyl)-isoindolin-1,3-dione and 2.8 ml (55.6 mmol) hydrazine.hydrate.

Sources & evidence

ORD record
ord-b32b8562d5a54520b1edcbb0ad0953a1
Source dataset
uspto-grants-2005_06
Patent number
US06903118B1

Reaction notes

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