HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Tert-butyl 4-(2-(1,3-dioxoisoindolin-2-YL)ethyl)piperazine-1-carboxylate | HCID 22397705 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate | HCID 1514400 | — |
Reaction Steps
Batch size: 42.2 g (120 mmol) 2-{2-[4-(tert-butoxycarbonyl)-piperazin-1-yl]-ethyl}-isoindolin-1,3-dione and 11.6 ml (240 mmol) hydrazine-hydrate in 450 ml ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06903118B1 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-8df366f37a394da6a6d020f0fc60252c |
| Source note | uspto-grants-2005_06 |