Lithium Hydroxide → 6-[[1-Phenyl-2-propylmercapto-1H-benzimidazol-6-yl]oxy]Hexanoic Acid
Reaction equation
C[O:2][C:3](=[O:29])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]2[N:17]=[C:16]([S:18][CH2:19][CH2:20][CH3:21])[N:15]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[C:14]=2[CH:28]=1.[OH-].[Li+]>>[C:22]1([N:15]2[C:14]3[CH:28]=[C:10]([O:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:29])=[O:2])[CH:11]=[CH:12][C:13]=3[N:17]=[C:16]2[S:18][CH2:19][CH2:20][CH3:21])[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1Participants
3
Procedure
109 mg of 6-[[1-phenyl-2-propylmercapto-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl ester was reacted according to general operating instructions 3 with lithium hydroxide. 104 mg was obtained.
Workup
- custom104 mg was obtained
Sources & evidence
- ORD record
- ord-d6970d593c664fbcb4adb42377779d1b
- Source dataset
- uspto-grants-2005_06
- Patent number
- US06903126B2
Reaction notes
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