2-Methylhexanoic Acid → 5-{N'-(2-methylhexanoyl)-L-alaninyl}-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

HRID 1071435Notes

Reaction equation

HRID 1071435 reaction equation
[CH3:1][CH:2]([CH2:6][CH2:7][CH2:8][CH3:9])[C:3](O)=[O:4].[NH2:10][C@H:11]([C:13]([N:15]1[C:21](=[O:22])[CH:20]([CH3:23])[C:19]2[CH:24]=[CH:25][CH:26]=[CH:27][C:18]=2[C:17]2[C:28]([NH2:32])=[CH:29][CH:30]=[CH:31][C:16]1=2)=[O:14])[CH3:12]>>[CH3:1][CH:2]([CH2:6][CH2:7][CH2:8][CH3:9])[C:3]([NH:10][C@H:11]([C:13]([N:15]1[C:21](=[O:22])[CH:20]([CH3:23])[C:19]2[CH:24]=[CH:25][CH:26]=[CH:27][C:18]=2[C:17]2[C:28]([NH2:32])=[CH:29][CH:30]=[CH:31][C:16]1=2)=[O:14])[CH3:12])=[O:4]

Participants

3

Reactant 2

HCID 206532-Methylhexanoic AcidHCID 697363355-(L-alaninyl)-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

Product 1

HCID 865925935-{N'-(2-methylhexanoyl)-L-alaninyl}-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

Procedure

Following General Procedure C-P above using 2-methylhexanoic acid and 5-(L-alaninyl)-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one, as described in Example 7-B, the title compound was prepared. The molecular weight as determined by mass spectrometry (FD) was: 422 (M+H).

Sources & evidence

ORD record
ord-8a59454484f24296a6696bc1d66ee1fe
Source dataset
uspto-grants-2005_06
Patent number
US06906056B2

Reaction notes

Loading…