Diethyl Ether → HCID 178488143, compound

HRID 1071544Notes

Reaction equation

HRID 1071544 reaction equation
[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]2[NH:7][C:8]([S:10][CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[C:13]=3[NH2:19])=[N:9][C:5]=2[CH:4]=1.C([O:24]CC)C>>[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]2[NH:7][C:8]([S:10]([CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[C:13]=3[NH2:19])=[O:24])=[N:9][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 3283Diethyl EtherHCID 178488115HCID 178488115, compound

Product 1

HCID 178488143HCID 178488143, compound

Procedure

The title compound was prepared by the method of Example 3 using 2.00 g of the title product of Example 35 instead of the title product of Example 2. Trituration with diethylether gave 1.58 g of the title compound: m.p. 142-144° C. Analysis. Calc'd. for C16H17N3O2S: C, 60.93; H, 5.43; N, 13.32; S, 10.17. Found: C, 60.60; H, 5.42; N, 12.83; S, 9.86.

Sources & evidence

ORD record
ord-30da31eeefa24360ac69215e2cffd2be
Source dataset
uspto-grants-2005_06
Patent number
US06906078B2

Reaction notes

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